In findings presented at the American Physiological Society’s Inflammation, Immunity and Cardiovascular Disease conference in Westminster, Colorado, it was shown that it is possible to reduce weight with gut bacteria therapy.
What research was undertaken?
People who are obese tend to produce less of a lipid produced by your small intestine. It is this lipid that helps to suppress your appetite and reduce inflammation.
During the study at the Vanderbilt University in Nashville, Tennessee, researchers incorporated engineered bacteria into the guts of mice, which helped prevent weight gain and the subsequent negative effects of obesity.
The researchers also gave the engineered bacteria to mice with an increased susceptibility to atherosclerosis and fatty liver disease.
They found that these mice gained less fat in their livers along with other markers that indicated less chance of experiencing liver disease.
Lead researcher Sean Davies, Associate Professor of Pharmacology at Vanderbilt University had this to say abut the findings:
“Some day in the future, it might be possible to treat the worst effects of obesity simply by administering these bacteria.”
“Our new studies focused on mice highly prone to develop atherosclerosis and fatty liver disease, and we showed that the engineered bacteria were beneficial not only in inhibiting obesity, but also in protecting against fatty liver disease and somewhat against atherosclerosis (hardening of the arteries).”
While impressive, it is worth remembering that these results were on lab mice, only time will tell if these same results can be replicated on any human studies.